Is it possible to od on st john wort

There were reports for Prozac. They include vomiting, dizziness, anxiety, panic attacks, aggression, and amnesia. There are also serious concerns about drug interactions. The flowers are used to make liquid extracts, pills, and teas. The popular herbal therapy is often used to ease symptoms of depression.

People have been using St. A Cochrane systematic review found that St. A review of 35 studies concluded that St. A analysis of 27 studies determined that St. Those researchers also noted that fewer people stopped taking St. Another study indicated St. However, the Food and Drug Administration FDA has not approved the substance for depression or any other medical condition. The FDA, in fact, classifies St. Jeremy Wolf, a licensed naturopathic physician, explained that St.

Wolf said St. Some may interact with medications you take. We have little safety information on St. Take charge of your health—talk with your health care providers about any complementary health approaches you use. Together, you can make shared, well-informed decisions. For More Information.

Toll-free in the U. MedlinePlus To provide resources that help answer health questions, MedlinePlus a service of the National Library of Medicine brings together authoritative information from the National Institutes of Health as well as other Government agencies and health-related organizations. Depression Toll-free in the U. Key References. De Smet PA. Herbal remedies. New England Journal of Medicine. Hypericum Depression Trial Study Group.

Effect of Hypericum perforatum St. Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review.

Nutrition Journal. Complementary and alternative medicine usage for behavioral health indications. Primary Care. Linde K. Cochrane Database of Systematic Reviews. Regardless of its status as an herbal dietary supplement, St. John's Wort is a drug. Its active ingredients, hypericin and pseudohypericin, are isolated from Hypericum perforatum. It is known to have medicinal properties, including antidepressant, antimicrobial, and antiviral effects. Nearly prescription drugs are known to interact with St.

As with many other drugs, St. Through its activity on the cytochrome P metabolism system it can also severely decrease the effectiveness of many medications, including immunosuppressants and drugs used to treat high blood pressure and high cholesterol. Classified as an OTC herbal supplement, St. Furthermore, the packaging of St. Randomized control trials examining the efficacy of St.

Some placebo-controlled trials have shown only marginal benefit, while others found beneficial effects similar to those of prescription antidepressants.

Free E-newsletter Subscribe to Housecall Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Sign up now. Show references St. National Center for Complementary and Integrative Health.

Accessed Jan. Natural Medicines. IBM Microdemex. Kellerman RD, et al. Popular herbs and nutritional supplements. In: Conn's Current Therapy Elsevier;